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Computational Fluid Dynamics Simulation
CFD (Computational Fluid Dynamics) simulation is a highly effective tool for an analysis of fluid phenomena, which enables a detailed verification of various properties in mixing vessels. At the same time, these CFD technologies are well integrated with the reliable technical know-how and expertise supported by a wide variety of experiments, and the abundant experience in design and performance analysis of commercial process equipment. This technology, applied for pharmaceuticals production, realizes the optimal design and appropriate scaling-up of various types of mixing vessels, including chemical reactors, bioreactors, and crystallizers.
         
Features
  • Fluid properties including fluid velocity, pressure, and shear stress.
  • Gas dispersion and gas hold-up in an aerated mixing vessel as well as particulate dispersion in solid-liquid and liquid-emulsion systems.
  • Chemical reaction, concentration distribution of chemical species.
    With appropriate models, CFD is applicable to liquid-liquid, gas-liquid and solid-liquid systems.

Applications

Applied example for a continuously aerated bioreactor

 

Experience
   
  • Large-scale mammalian cell culture system of several thousand liter size (Mass transfer)
  • Chemical reaction system of several thousand liter size (Aerated mixing)
  • Crystallization system (Fluid flow)
  • Microbial culture system (Non-newtonian fluid)
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